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Dermal Health and Aesthetics

Things to know before injecting Rejuran to avoid disillusionment

Dr. Quynh Trang – Specialist in Dermatology HCMCJun 20, 20256 min read
Things to know before injecting Rejuran to avoid disillusionment

Rejuran has earned the nickname “elixir” among beauty enthusiasts, leading some to mistakenly believe that a single treatment will instantly rejuvenate them. In reality, its effectiveness depends on various objective factors, such as an individual’s skin condition and the treatment process used. Review these three essential points before getting Rejuran injections to avoid disappointment from results that don’t meet expectations.

Rejuran Injections Don’t Make You Look Younger Instantly

Even though Rejuran uses salmon DNA extract with up to 97% biocompatibility, it cannot make you look younger right after injection. This is because PN (Polynucleotide), Rejuran’s primary component, requires time to activate its regenerative, repair, and regenerative functions of fibroblasts, enhance collagen synthesis, strengthen the ECM (Extracellular Matrix), and create a favorable environment for new cell production and growth.

Generally, noticeable changes can be observed one to two weeks after the first treatment session. When touching the skin, you’ll feel improvements in texture, texture, hydration, and elasticity.

Moreover, to achieve radiant, dewy skin, you must adhere to the complete treatment course tailored to your needs. The effects of each session accumulate and become more pronounced with subsequent treatments. Stopping after one session may lead to results that fall short of expectations.

những điều cần biết trước khi tiêm rejuran

Rejuran injections don’t deliver instant rejuvenation; results accumulate gradually with each session.

Learn about Rejuran Healer – A skin regeneration product from Rejuran

Rejuran’s Rejuvenation Effects Are Temporary

After a Rejuran treatment course, regenerated skin becomes vibrant, firmer, and more even-toned for up to 6 months. This is thanks to PN (Polynucleotide) stimulating fibroblasts and activating the skin’s natural functions. Additionally, with the unique Scaffold 3D structure and DOT™️ PN technology, it creates a voluminous, porous effect through supportive frameworks, providing an optimal environment for cell and tissue growth.

However, biological aging cannot be halted, and signs of aging will reappear over time. Combined with lifestyle and post-treatment skincare, the duration and extent of the effects will vary.

những điều cần biết trước khi tiêm rejuran

No rejuvenation treatment offers lifelong results after one session, and Rejuran is no exception.

Rejuran Is Not Suitable for Everyone

No treatment can achieve optimal results without appropriate indications. Rejuran’s remarkable rejuvenation capabilities do not yield consistent results across all age groups.

If you’re in your late teens or early twenties with youthful, plump skin showing minimal signs of aging or damage, and your skin is healthy, you’re unlikely to notice significant changes after using Rejuran.

If you’re over 35, with skin showing signs of aging such as fine wrinkles, dryness, loss of elasticity, or damage from sun exposure or improper skincare, making it more sensitive, you’re an ideal candidate for Rejuran. Post-treatment, your skin will appear naturally taut without stiffness, with added hydration from within, becoming softer. The contrast between before and after injections will highlight the significant value of this rejuvenation method.

những điều cần biết trước khi tiêm rejuran

Rejuran struggles to “prove itself” with younger individuals who have few wrinkles.

If you’re over 50 with pronounced aging signs like deep wrinkles, folds, or significant sagging, volumizing fillers or skin-tightening technologies may be prioritized over Rejuran alone.

Thus, before treatment, doctors typically assess the skin condition to determine if the individual is truly suitable for the therapy, helping balance expectations with outcomes.

Key Considerations to Enhance Rejuran’s Effectiveness

Rejuran can address 10 skin concerns, such as improving elasticity, restoring the skin barrier, enhancing tone, and evening complexion, if given the right conditions to maximize its strengths.

Choosing Suitability Based on Specific Skin Conditions

Rejuran is ideal for:

– Rough, dehydrated, less elastic skin with enlarged pores.

– Loose, sagging, less firm skin texture.

– Dull, lifeless skin.

– Thin, sensitive skin needing restoration.

– Imbalanced oil-water levels on the skin.

– Individuals over 30 seeking regeneration, natural rejuvenation, and long-term skin healing.

– Skin undergoing invasive treatments or post-rejuvenation, regeneration, or high-tech device-based procedures.

– Dehydrated skin around the eyes needing structural improvement and radiance.

– Atrophic or pitted scars from acne or injuries, and post-invasive treatment cases.

Correct Injection Technique

những điều cần biết trước khi tiêm rejuran

Rejuran injections require expertise, precision, and accuracy in every step.

Rejuran injections must ensure proper technique, target layer, dosage, and density on the skin.

As we know, Rejuran works by promoting cell growth through fibroblast stimulation, activating the production of essential dermis components like collagen and strengthening the ECM. Since fibroblasts reside in the dermis, Rejuran should be delivered and deposited in this layer for optimal stimulation and regeneration.

– Depth and technique: Intradermal (within the skin).

– Dosage (per point): 0.02–0.05 mL.

– Injection spacing: 0.5–1 cm between points.

Additionally, treatment should focus on specific problem areas like loose texture, dehydration, or lack of firmness.

To achieve high precision and consistency in each injection, Rejuran therapy must be performed by highly skilled dermatologists. Only when placed correctly can Rejuran actively strengthen skin structure and restore vitality.

Combining Multiple Therapies

Rejuran is versatile and proactive, capable of being combined with various treatments to enhance efficacy and ensure comprehensive post-procedure skin recovery. Rejuran creates a “priming reaction” to condition the skin before additional complementary treatments.

With high-tech devices, Rejuran supports pre- and post-treatment for invasive procedures like laser, CO2 fractional, or heat-based rejuvenation with Thermage, HIFU, RF, and more.

Moreover, Rejuran pairs well with wrinkle-erasing Botox, meso Botox, volumizing fillers, eye rejuvenation, or scar treatments post-subcision, CO2 fractional laser, or dermaroller procedures.

Related Questions

Question 1: Does Rejuran provide immediate results after injection?

No. Rejuran does not deliver instant rejuvenation post-injection. Its main component, Polynucleotide (PN), requires time to activate fibroblast functions, boost collagen production, and regenerate skin. Visible skin improvements typically appear 1–2 weeks after the first session, accumulating with subsequent treatments.

Question 2: How long do Rejuran’s rejuvenation effects last?

Rejuran’s effects typically last about 6 months. During this period, skin becomes firmer, more even-toned, and healthier due to PN-stimulated regeneration. However, the duration depends on biological age, lifestyle, and post-treatment skincare.

Question 3: Who is the most suitable candidate for Rejuran?

Rejuran is best for individuals over 30 with aging signs like dryness, loss of elasticity, fine wrinkles, or sun-damaged or improperly cared-for skin. For those under 20 with healthy skin or over 50 with deep aging signs, Rejuran may not yield noticeable results or may require a combination with other methods.

Question 4: How should Rejuran be injected for optimal results?

Rejuran requires precise intradermal injection with 0.02–0.05 mL per point, spaced 0.5–1 cm apart. Injecting into the dermis, where fibroblasts reside, maximizes collagen production and structural reinforcement. This should be performed by specialized dermatologists for safety and efficacy.

Question 5: Can Rejuran be combined with other treatments?

Yes. Rejuran is highly versatile and often combined with treatments like laser, HIFU, RF, Botox, fillers, or scar therapies. When combined correctly, Rejuran primes the skin, enhancing efficacy and accelerating recovery post-invasive procedures.

Conclusion

Rejuran’s effectiveness depends not only on the product but also on proper treatment protocols, execution techniques, and individual skin conditions. A personalized course by experienced specialists will allow Rejuran to maximize its inherent benefits, delivering naturally healthy, radiant skin over time. Therefore, before deciding on treatment, research thoroughly, seek professional advice, and set expectations based on a clear understanding of the product’s mechanism. Don’t expect miracles after a single injection, as true beauty requires time to blossom.

Dr. Quynh Trang – Specialist in Dermatology HCMC
Medically reviewed by

Dr. Quynh Trang – Specialist in Dermatology HCMC

  • Over 12 years of experience in dermatology and aesthetic medicine
Dr. Tran Quynh Trang holds multiple certifications in acne scar treatment, injection techniques, laser and light-based applications, dermatologic procedures, and various other professional qualifications.
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